Related Experiment Video
Updated: Feb 11, 2026

Formation of Dispersible Taohong Siwu Tablets
Published on: February 3, 2023
Cyclodextrins as excipients in tablet formulations
Jaime Conceição1, Oluwatomide Adeoye2, Helena Maria Cabral-Marques3
1UCIBIO - ReQuimTe, Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, Oporto, Portugal.
Abstract:
This paper aims to provide a critical review of cyclodextrins as excipients in tablet formulations, highlighting: (i) the principal pharmaceutical applications of cyclodextrins; (ii) the most relevant technological aspects in pharmaceutical formulation development; and (iii) the actual regulatory status of cyclodextrins. Moreover, several illustrative examples are presented. Cyclodextrins can be used as complexing excipients in tablet formulations for low-dose drugs. By contrast, for medium-dose drugs and/or when the complexation efficiency is low, the methods to enhance the complexation efficiency play a key part in reducing the cyclodextrin quantity. In addition, these compounds are used as fillers, disintegrants, binders and multifunctional direct compression excipients of the tablets.
Related Concept Videos
Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules
Pharmaceutical Alternatives: Excipients and Impurities-Related Therapeutic Nonequivalence
Cartesian Form for Vector Formulation
Resultant Moment: Vector Formulation
The resultant moment of a system of forces can be calculated through vector formulation. For example, if we consider...
Couples: Scalar and Vector Formulation
A couple moment is a rotational force that tends to rotate the steering wheel. The wheel's rotation can either be in a clockwise or anticlockwise direction. The right-hand rule is a helpful method for determining the direction of a couple moment....
Formulating and Validating Nursing Diagnosis I
There are thirteen domains...

