[Investigation on the prevalence of hyperuricemia among young students]

Objective: To investigate the prevalence of hyperuricemia and the distribution of serum uric acid in young students. Methods: Determination of 14 214 cases of freshmen, 3 072 cases of the graduate and 6 804 cases of school staff in 2015-2016 from one University of Beijing with uric acid (UA) enzymatic method, hyperuricemia criteria for male UA >420 μmol/L, female UA >357 μmol/L, were grouped according to age. From freshmen in 2016 randomly selected 1 782 cases men and 1 175 cases women through the questionnaire to investigate the prevalence of gout. Results: The prevalence of hyperuricemia in male and female freshmen were 34.47% (1 958/5 681) and 11.64% (993/8 533) respectively. The prevalence of hyperuricemia in male and female graduates were 32.73% (381/1 164) and 10.06% (192/1 908) respectively. In the same period, the prevalence of hyperuricemia was 14.42% (480/2 844) among male workers and 9.92% (393/3 960) among female workers. The blood uric acid level was analyzed among the freshmen in 2015-2016 and the graduates in 2015, most freshmen were 420-480 μmol/L in males and 357-480 μmol/L in females. The prevalence of gout was 0.34% (6/1 782) in males and 0.26% (3/1 175) in females respectively (which had at least one attack of the first metatarsophalangeal joint and non-traumatic articular pain and swelling of the knee). In addition, there was no significant difference in the prevalence of hyperuricemia in coastal and inland areas (P>0.05). There was significant difference in the proportion of BMI in male and female newborns with hyperuricemia (P<0.05). Conclusion: The young men of high uric acid hematic disease prevalence showed a trend of increased significantly, male and female serum UA value most in mild-to-moderate elevated levels, and a lower incidence of gout. Compared with the general population, BMI of the freshmen with hyperuricemia increased significantly.