Related Experiment Video
Updated: Feb 11, 2026

The HoneyComb Paradigm for Research on Collective Human Behavior
Published on: January 19, 2019
Operation Change: A New Paradigm Addressing Behavior Change and Musculoskeletal Health Disparities
Lynne C Jones1, Yashika Watkins2, Duanny Alva3
1Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. ljones3@jhmi.edu.
Background:
In this study, we examined the implementation and efficacy of Operation Change, a community-based, culturally sensitive program to stimulate behavioral changes in activity level and improve musculoskeletal health in African-American (AA) and Hispanic/Latina (H/L) women with obesity and early-stage osteoarthritis.
Methods:
Sixty-two women (32 AA and 30 H/L), 40-75 years old, with nontraumatic knee pain and body mass index values > 30, participated in a 12-week program of presentations, motivational interviewing, goal setting, and physical activities. Assessments (at 0, 6, and 12 weeks) included a demographic questionnaire, physical assessment, timed 50-ft walking test, Western Ontario and McMaster Universities Arthritis Index (WOMAC), Short Form-36 Health Survey (SF-36), 8-Item Physical Health Questionnaire (PHQ-8), and motivational interview assessment.
Results:
Walking time improved significantly for H/L women (P < 0.0001) but not AA women (P = 0.0759). Both groups had significant mean weight loss (P < 0.05) with high variability among individuals. WOMAC scores for both groups indicated decreased pain (P < 0.0001) and stiffness (P < 0.0001) and improved physical functioning (P < 0.0001) by 12 weeks. SF-36 results were comparable to those of the WOMAC. PHQ-8 results improved significantly for H/L women (P < 0.0001) but not AA women (P = 0.077). Participants scored the motivational interviewing component of the program favorably.
Conclusions:
Participation in Operation Change increased physical activity, resulting in improvements in pain and function scores. This supports a new paradigm for behavioral modification that helps AA and H/L women take an active role in living with osteoarthritis.
Related Concept Videos
Global Climate Change
Rates of Change
Work Done During Volume Change
Consider a gas confined to a cylinder fitted with a movable piston at one end. If the gas expands from volume V1 to volume V2, it exerts a force on the piston, such that the piston moves by a distance dr.
The work done by the gas on the piston can be expressed as
Le Chatelier's Principle: Changing Temperature
To understand this phenomenon, consider the elementary reaction:
Standard Entropy Change for a Reaction
Unsoundness of Aggregate due to Volume Change

