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Updated: Feb 11, 2026
07:05
Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
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Perivascular Leiomyomatosis: A Unique Case Report.
Scott Wolfe1, James Sullivan1, Leonard Kahn1
11 Northwell Health, Lake Success, NY, USA.
International Journal of Surgical Pathology
|April 26, 2018
Summary
This study documents a unique case of perivascular leiomyomatosis, a rare benign smooth muscle neoplasm. The findings differentiate it from intravascular leiomyomatosis, highlighting a novel presentation of smooth muscle tumors.
Area of Science:
- Pathology
- Oncology
- Surgical Pathology
Background:
- Benign smooth muscle neoplasms can exhibit unusual growth patterns, including intravascular leiomyomatosis, benign metastasizing leiomyoma, and leiomyomatosis peritonealis disseminata.
- Accurate classification of these rare entities is crucial for appropriate patient management.
Observation:
- A unique case of perivascular leiomyomatosis is presented.
- The tumor demonstrated multiple nodules of benign smooth muscle.
- These nodules were associated with the outer surface of venous channels, specifically the medial muscle layer.
Findings:
- The neoplastic nodules' location on the outer venous surface distinguishes this entity from intravascular leiomyomatosis.
- Histological examination confirmed benign smooth muscle differentiation.
- This presentation represents a novel growth pattern for benign smooth muscle neoplasms.
Implications:
- This case expands the spectrum of recognized benign smooth muscle neoplasms with unusual growth patterns.
- It underscores the importance of precise histological evaluation to differentiate rare entities.
- Further research may elucidate the pathogenesis and clinical behavior of perivascular leiomyomatosis.
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