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Updated: Feb 11, 2026

Experimental Procedure for Laboratory Studies of In Situ Burning : Flammability and Burning Efficiency of Crude Oil
Published on: May 1, 2018
Study of the plasma proteome of Atlantic cod (Gadus morhua): Changes due to crude oil exposure
Karianne S Enerstvedt1, Magne O Sydnes2, Daniela M Pampanin1
1International Research Institute of Stavanger (IRIS) - Environment Department, Mekjarvik 12, NO-4070 Randaberg, Norway; Faculty of Science and Technology, Department of Chemistry Bioscience and Environmental Engineering, University of Stavanger, NO-4036 Stavanger, Norway.
Abstract:
Oil contamination is an environmental issue of great concern and the necessity for background studies and monitoring programs to continuously evaluate the levels of oil pollution is required. In this study, Atlantic cod (Gadus morhua) were exposed to dispersed crude oil for 1 and 4 weeks to simulate environmental contamination. Fractionated plasma samples were then analysed by tandem mass spectrometry. In total, 717 proteins were identified and 10 new protein biomarker candidates were found. The significant proteome changes were related to the immune response by alterations in the levels of specific immunoglobulins, alpha-2-macroglobulin and galectin-3-binding proteins. After 4 weeks of oil exposure, a lowered level of a NLRC3-like protein was also observed. The results from this study provide insight into the Atlantic cod plasma proteome and into the toxicological effects and potential response mechanisms of short and long-term exposure to crude oil.
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