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FACS-Isolation and Culture of Fibro-Adipogenic Progenitors and Muscle Stem Cells from Unperturbed and Injured Mouse Skeletal Muscle
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Ameloblastic fibro-odontoma with chondroid tissue formation
Noura Aly1, Hatem Amer2, Omar El Khatib2
1Faculty of Dentistry, Cairo University, Egypt.
Contemporary Oncology (Poznan, Poland)
|April 26, 2018
Summary
This study details an unusual case of ameloblastic fibro-odontoma (AFO) in a child, noting the rare presence of chondroid tissue. The benign odontogenic tumor was surgically removed and has not recurred.
Area of Science:
- Oral and Maxillofacial Pathology
- Pediatric Dentistry
- Odontogenic Tumors
Background:
- Ameloblastic fibro-odontoma (AFO) is a rare, benign mixed odontogenic tumor typically affecting children and adolescents.
- This report focuses on an atypical AFO presentation in a five-year-old male with mandibular involvement.
Observation:
- A large, multilocular radiolucency with radiopaque deposits was observed on CT scans.
- Histopathological examination revealed characteristic AFO components alongside significant chondroid (cartilaginous) tissue formation.
- Immunohistochemistry aided in differentiating the origins of the diverse odontogenic tissues.
Findings:
- The study presents the first documented case of ameloblastic fibro-odontoma exhibiting chondroid tissue formation.
- Surgical excision was successful, with no recurrence observed during follow-up.
- Immunohistochemical markers (cytokeratin, vimentin, s-100) were crucial for diagnosis.
Implications:
- This case expands the known histopathological spectrum of ameloblastic fibro-odontoma.
- Highlights the importance of comprehensive histopathological and immunohistochemical analysis in diagnosing rare odontogenic lesions.
- Suggests that chondroid differentiation may occur in AFO, warranting further investigation.
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