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Published on: June 10, 2025
The decrease in phase angle measured by bioelectrical impedance analysis reflects the increased locomotive syndrome
Satoshi Tanaka1, Kei Ando1, Kazuyoshi Kobayashi1
1a Department of Orthopaedic Surgery , Nagoya University Graduate School of Medicine , Nagoya , Japan.
Phase angle, a measure of cellular health, is a better indicator of locomotive syndrome (LS) risk than muscle mass. Lower phase angle significantly correlates with increased LS risk stages, suggesting its utility as a screening tool.
Area of Science:
- Gerontology
- Biomedical Engineering
- Physical Medicine
Background:
- Locomotive Syndrome (LS) risk assessment is crucial for evaluating physical ability.
- Phase angle, measured by bioelectrical impedance analysis (BIA), reflects cellular health and muscle mass.
- The relationship between phase angle, muscle mass, and LS risk stages requires further investigation.
Purpose of the Study:
- To investigate the association between muscle mass, phase angle, and Locomotive Syndrome (LS) risk stages.
- To compare the efficacy of phase angle and muscle mass as indicators of LS risk.
Main Methods:
- A prospective cohort study involving 311 participants undergoing health checkups.
- Assessment of LS risk using the two-step test, stand-up test, and 25-question geriatric locomotive function scale.
- Measurement of muscle mass and phase angle via bioelectrical impedance analysis (BIA).
Main Results:
- Phase angle significantly decreased with advancing LS risk stages.
- Muscle mass did not show a significant difference across LS risk stages, particularly between no risk and stage 1.
- Adjusted analyses confirmed phase angle's significant difference across all LS risk stages.
Conclusions:
- Phase angle is a stronger indicator of LS risk than muscle mass.
- Significantly reduced phase angle is observed in later LS risk stages.
- Phase angle serves as a valuable screening tool for identifying individuals at risk of Locomotive Syndrome.
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