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Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Andrew J Admon1,2, Ashwin Gupta3,4, Margaret Williams5
1Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA. ajadmon@umich.edu.
The evidence supporting Choosing Wisely® recommendations varies, with many citing clinical practice guidelines (CPGs) or lower-quality data. This study analyzed the evidence strength for these important healthcare recommendations.
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