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Thrombosis in Thyroid Cancer
Arash Ordookhani1, Abbas Motazedi1, Kenneth D Burman2
1MD, Endocrine Section, Department of Internal Medicine, Providence Hospital, Washington, DC, 20017.
International Journal of Endocrinology and Metabolism
|April 27, 2018
Summary
Venous thromboembolism (VTE) risk in thyroid cancer patients is unclear, with limited and conflicting studies. Further research is needed to determine if anticoagulants are necessary for certain thyroid cancer groups.
Area of Science:
- Endocrinology
- Oncology
- Hematology
Background:
- Limited and contradictory studies exist on venous thromboembolism (VTE) in thyroid cancer patients.
- Existing data on the association between VTE and thyroid cancer are scarce and inconclusive.
Purpose of the Study:
- To review the current literature on venous thromboembolism (VTE) in patients with thyroid cancer.
- To synthesize existing evidence regarding the relationship between thyroid cancer and VTE risk.
Main Methods:
- Comprehensive literature review using MEDLINE database.
- Keywords included terms related to coagulation, hemostasis, bleeding, and various thyroid cancer subtypes.
- Inclusion criteria focused on studies examining changes in hemostasis and thyroid cancer.
Main Results:
- Some studies suggest a potential increase in VTE occurrence in thyroid cancer patients aged 60 and above, particularly near diagnosis.
- Other studies found no significant difference in VTE rates compared to the general population.
- Changes in thyroid cancer classification may influence future VTE association studies.
Conclusions:
- Prospective studies are necessary to investigate VTE occurrence across different thyroid cancer types, severities, and age groups.
- Results could inform clinical practice regarding anticoagulant use in specific thyroid cancer patient cohorts.
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