Related Experiment Video
Updated: Feb 11, 2026
Development and Evaluation of 3D-Printed Cardiovascular Phantoms for Interventional Planning and Training
Published on: January 18, 2021
CREATE Wellness: A multi-component behavioral intervention for patients not responding to traditional Cardiovascular
Chris Miller-Rosales1, Stacy A Sterling2, Sabrina B Wood2
1University of California at Berkeley, Berkeley, CA, USA.
Insights
A new group intervention, CREATE Wellness, targets patients with persistent cardiovascular disease risk factors. This evidence-based approach aims to improve risk factor control for those not benefiting from traditional management.
Area of Science:
- Cardiovascular disease research
- Behavioral intervention science
- Health services research
Background:
- Cardiovascular disease (CVD) is a leading cause of mortality in the US.
- Many patients do not achieve optimal CVD risk reduction with traditional management strategies.
- A significant patient group persistently fails to meet CVD risk factor control goals.
Purpose of the Study:
- To describe the rationale, development, and implementation of a novel multi-component behavioral intervention.
- To target patients with persistent sub-optimal control of CVD risk factors.
- To address the complex needs of individuals with elevated or unmeasured CVD-related risk factors.
Main Methods:
- Developed the group-based "CREATE Wellness" intervention using evidence, theory, stakeholder input, and patient feedback.
- Testing the intervention in a randomized trial involving patients with over 2 years of sub-optimal risk factor control.
- Intervention integrates patient activation, health system engagement, shared decision-making, care planning, and barrier identification.
Main Results:
- The CREATE Wellness intervention is a 3-session group program.
- Combines evidence-based elements to address patient needs and barriers to care.
- Key learnings emphasize stakeholder input and pragmatic skills training.
Conclusions:
- CREATE Wellness offers an evidence-based, patient-centered alternative for patients unresponsive to traditional disease management.
- The randomized trial is ongoing at Kaiser Permanente Northern California.
- Future steps include efficacy evaluation and adaptations for diverse populations and delivery modes.
Background/Aims:
Cardiovascular disease (CVD) is the leading cause of death in the US. Many patients do not benefit from traditional disease management approaches to CVD risk reduction. Here we describe the rationale, development, and implementation of a multi-component behavioral intervention targeting patients who have persistently not met goals of CVD risk factor control.
Methods:
Informed by published evidence, relevant theoretical frameworks, stakeholder advice, and patient input, we developed a group-based intervention (Changing Results: Engage and Activate to Enhance Wellness; "CREATE Wellness") to address the complex needs of patients with elevated or unmeasured CVD-related risk factors. We are testing this intervention in a randomized trial among patients with persistent (i.e > 2 years) sub-optimal risk factor control despite being enrolled in an advanced and highly successful CVD disease management program.
Results:
The CREATE Wellness intervention is designed as a 3 session, group-based intervention combining proven elements of patient activation, health system engagement skills training, shared decision making, care planning, and identification of lifestyle change barriers. Our key learnings in designing the intervention included the value of multi-level stakeholder input and the importance of pragmatic skills training to address barriers to care.
Conclusions:
The CREATE Wellness intervention represents an evidence-based, patient-centered approach for patients not responding to traditional disease management. The trial is currently underway at three medical facilities within Kaiser Permanente Northern California and next steps include an evaluation of efficacy, adaptation for non-English speaking patient populations, and modification of the curriculum for web- or phone-based versions.
Clinicaltrialsgov Identifier:
NCT02302612.
Related Concept Videos
01:27Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
01:21Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
01:29Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
01:26Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
01:21Rheumatic Heart Disease III: Medical Management
01:23Peripheral Artery Disease V: Postoperative Nursing Management