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Benzothiazole analogs as potential anti-TB agents: computational input and molecular dynamics

Katharigatta N Venugopala1,2, Mohammed A Khedr1,3, Melendhran Pillay4

  • 1a Department of Pharmaceutical Sciences, College of Clinical Pharmacy , King Faisal University , Al-Ahsa , 31982 , Kingdom of Saudi Arabia.

Journal of Biomolecular Structure & Dynamics
|April 27, 2018
PubMed

Keywords:
BenzothiazoleDAPA: 7,8-diamino pelargonic acid aminotransferaseH37RvMDR-MTBMDR-MTB: multidrug-resistant strains ofMIC: minimum inhibitory concentrationPLP: Pyridoxal phosphateSAM: S-adenosylmethionineXDR-MTB: extensively drug-resistantminimum inhibitory concentrationsingle crystal X-ray studies

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