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Updated: Feb 11, 2026

Author Spotlight: Porphyrin-Modified Beads for Use as Compensation Controls in Flow Cytometry
Published on: March 24, 2023
Investigation and Control of Single Molecular Structures of Meso- Meso Linked Long Porphyrin Arrays
Sang Hyeon Lee, Sujin Ham, Seungsoo Nam
1Department of Chemistry, Graduate School of Science , Kyoto University , Sakyo-ku, Kyoto 606-8502 , Japan.
Abstract:
We have investigated conformational structures of meso- meso linked porphyrin arrays (Z n) by single molecule fluorescence spectroscopy. Modulation depths ( M values) were measured by excitation polarization fluorescence spectroscopy. The M value decreases from 0.85 to 0.46 as the number of porphyrin units increases from 3 to 128, indicating that longer arrays exhibit coiled structures. Such conformational changes depending on the length have been confirmed by coarse-grained simulation. The histograms of M values and traces of centroid position of emitting sites by localization microscopy showed that the structures of longer arrays changed to more stretched after solvent vapor annealing with tetrahydrofuran.
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