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A Hyeda1, E S M da Costa2

  • 1Instituto Superior de Administração e Economia - Fundação Getúlio Vargas (ISAE/FGV).

Value in Health Regional Issues
|April 27, 2018
PubMed
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Chemotherapy preparation generates significant toxic waste, averaging 11.96% per application. Factors like treatment protocol and dosage forms contribute to this chemotherapy waste, impacting disposal needs.

Area of Science:

  • Oncology
  • Environmental Health
  • Pharmaceutical Sciences

Context:

  • Chemotherapy is a critical cancer treatment.
  • Preparation of chemotherapy often involves discarding unused medication.
  • This discarded medication constitutes toxic waste, posing environmental and economic challenges.

Purpose:

  • To quantify and analyze chemotherapy waste generated during the drug preparation process.
  • To identify factors contributing to the production of chemotherapy waste.

Summary:

  • A cross-sectional study analyzed 1,289 intravenous chemotherapy prescriptions for 106 cancer patients.
  • Total chemotherapy residue produced was 63,824mg, averaging 602mg per user and 49mg per application.
  • The average chemotherapy waste percentage was 11.96%, with individual cases ranging from 0% to 50%.
Keywords:
Drug TherapyGood Manipulation PracticesHealth Services AdministrationMedical WasteNeoplasm

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Impact:

  • Findings highlight the significant volume of chemotherapy waste generated.
  • Identified factors include treatment protocol, dosage forms, and lack of dose rounding.
  • Results can inform strategies to minimize waste and improve resource utilization in cancer care.