Related Experiment Video
Updated: Feb 11, 2026
10:49
Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
9.4K
Three Rotavirus Outbreaks in the Postvaccine Era - California, 2017
MMWR. Morbidity and Mortality Weekly Report
|April 27, 2018
Summary
Rotavirus vaccines significantly reduced severe illness, but outbreaks still occur, even in vaccinated children. Continued emphasis on rotavirus vaccination is crucial for disease prevention in the U.S.
Area of Science:
- Pediatrics
- Infectious Diseases
- Vaccinology
Background:
- Rotavirus was a leading cause of severe diarrhea in U.S. children before vaccine introduction in 2006.
- Licensed rotavirus vaccines show high effectiveness (78%-89%) against moderate to severe illness, reducing overall prevalence.
- Rotavirus vaccine series completion (73%) lags behind other routine childhood vaccines (95%).
Purpose of the Study:
- To describe rotavirus activity and outbreaks in the post-vaccine era.
- To analyze the characteristics of recent rotavirus outbreaks in California.
Main Methods:
- Retrospective analysis of rotavirus outbreaks reported in California in 2017.
- Description of case demographics, illness severity, and vaccination status.
Main Results:
- Three rotavirus outbreaks occurred in California in 2017, including one fatality.
- Most cases presented with mild to moderate illness.
- Illness occurred across all age groups and affected vaccinated children.
Conclusions:
- Rotavirus activity persists in a biennial pattern despite widespread vaccination.
- Rotavirus vaccines are most effective against severe disease; mild/moderate infections can still occur.
- Continued emphasis on rotavirus vaccination is essential for reducing disease burden in the U.S.
Related Concept Videos
01:18Steps in Outbreak Investigation
596
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
596
02:22The Colonization of Land
37.8K
Changes in the environment of the early Earth drove the evolution of organisms. As prokaryotic organisms in the oceans began to photosynthesize, they produced oxygen. Eventually, oxygen saturated the oceans and entered the air, resulting in an increase in atmospheric oxygen concentration, known as the oxygen revolution approximately 2.3 billion years ago. Therefore, organisms that could use oxygen for cellular respiration had an advantage. More than 1.5 years ago, eukaryotic cells and...
37.8K