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Obesity

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...

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Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...

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Related Experiment Video

Updated: Feb 11, 2026

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Obesity and Ventricular Repolarization: a Comprehensive Review.

Jad Omran¹, Brian P Bostick¹, Albert K Chan¹

¹Division of Cardiovascular Medicine, University of Missouri, School of Medicine, Columbia, Missouri, USA.

Progress in Cardiovascular Diseases

|April 27, 2018

Summary

This summary is machine-generated.

Obesity is linked to sudden cardiac death, potentially due to delayed ventricular repolarization (VR). Weight loss in obese individuals effectively shortens the corrected QT interval (QTc) and reduces QT dispersion, improving cardiac electrical stability.

Keywords:

Obesity Overweight QT or QTc dispersion QTc Ventricular repolarization,electrocardiogram Weight loss

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Area of Science:

Cardiology
Obesity Medicine
Electrophysiology

Background:

Obesity is a significant risk factor for sudden cardiac death.
Delayed ventricular repolarization (VR) is a suspected mechanism linking obesity to cardiac events.
Electrocardiographic measures like corrected QT interval (QTc) and QT dispersion are used to assess VR.

Purpose of the Study:

To investigate the relationship between obesity and delayed ventricular repolarization.
To evaluate the impact of weight loss on VR parameters in obese individuals.
To explore potential co-morbidities associated with obesity that may influence VR.

Main Methods:

Review of controlled studies assessing QTc and QT dispersion in overweight/obese vs. normal weight individuals.
Analysis of studies examining the effects of weight loss (diet, bariatric surgery) on VR parameters.
Consideration of obesity-related co-morbidities (diabetes, hypertension, etc.) and their impact on VR.

Main Results:

Overweight and obese subjects exhibit significantly longer QTc and greater QT dispersion compared to normal weight controls.
Weight loss interventions (diet, bariatric surgery) lead to significant reductions in QTc and QT dispersion.
Obesity co-morbidities such as diabetes, hypertension, and heart failure may also delay VR.

Conclusions:

Obesity is associated with delayed ventricular repolarization, evidenced by prolonged QTc and increased QT dispersion.
Weight loss is an effective strategy to improve VR parameters in obese patients.
Further research is needed to determine if obesity is an independent predictor of delayed VR and if QTc prolongation sufficiently predisposes to fatal arrhythmias.