Low Grade Appendiceal Mucinous Neoplasm with Pseudomyxoma Peritonei: An Enigma for Pathologist

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Shagufta Qadri1, Kiran Alam1, Feroz Alam1

  • 1Department of Pathology, Jawaharlal Nehru Medical College, Aligarh, Uttar Pradesh, India.

Euroasian Journal of Hepato-Gastroenterology
|April 28, 2018
PubMed

Insights

Low-grade appendiceal mucinous neoplasms (LAMNs) can spread, causing pseudomyxoma peritonei. Early diagnosis of this rare appendiceal tumor is crucial for unpredictable outcomes.

Area of Science:

  • Gastroenterology
  • Oncology
  • Pathology

Background:

  • Malignant mucinous neoplasms of the appendix are rare.
  • Extra-appendiceal spread is a common cause of pseudomyxoma peritonei.
  • Early diagnosis of appendiceal neoplasms is critical.

Observation:

  • A 45-year-old male presented with abdominal distension, pain, and constipation.
  • Clinical examination and CT scan suggested pseudomyxoma peritonei.
  • Peroperative findings and histopathology confirmed low-grade appendiceal neoplasm.

Findings:

  • Low-grade appendiceal mucinous neoplasms (LAMNs) can spread beyond the appendix.
  • Pseudomyxoma peritonei can result from LAMN.
  • This case highlights the diagnostic challenges of rare appendiceal neoplasms.

Implications:

  • Increased vigilance for early diagnosis of LAMN is necessary.
  • Understanding LAMN spread is vital for managing pseudomyxoma peritonei.
  • Further research is needed due to limited information on LAMN.
Keywords:
Adenocarcinoma.AppendixMucinous neoplasmPseudomyxoma peritonei

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