[Research progress in renal injury relevant to primary Sjögren's syndrome]

Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease characterized by lymphoplasmacytic infiltration of the exocrine glands that results in multiple organs and systems damage. Renal injury affects 0.3%-27.0% patients. The most frequent form of nephropathy in pSS is tubulointerstitial nephritis. The main clinical manifestation is renal tubular acidosis. The renal prognosis in patients with pSS is usually favorable, but renal failure may occur. At present, it still lacks of strict consensus or guideline for the treatment.