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Updated: Feb 11, 2026

A Mouse Model of Direct Anastomosis via the Prespinal Route for Crossing Nerve Transfer Surgery
Published on: October 19, 2021
Nerve Transfer Surgery for Penetrating Upper Extremity Injuries
Efstathios Karamanos1, Ilya Rakitin2, Sophie Dream3
1Surgeon at Henry Ford Hospital in Detroit, MI. ekarama1@hfhs.org.
Context:
Nerve transfer surgery is an option for repair of penetrating injuries of the upper extremity. In the right setting, it has advantages over tendon transfers and nerve grafting.
Objective:
To review our experience since 2006 of nerve transfer surgery in the upper extremities.
Design:
We included cases performed to repair penetrating trauma within three months of injury with at least three years' follow-up.
Main Outcome Measures:
Preoperative and postoperative muscle strength of the affected extremity.
Results:
All 16 patients were males aged 16 to 43 years. Six patients underwent nerve transfer surgery because of elbow flexion; 5, finger extension; 3, finger flexion; and 2, wrist pronation. Nine patients (56%) had associated vascular injury, and 4 (25%) had fractures. Average follow-up was 6 years. No perioperative complications occurred. Patients had a mean of 3.7 operations after the initial trauma. All patients received physical therapy. All patients improved from 0 of 5 muscle strength preoperatively to a mean of 3.8 (range = 2/5 to 5/5) within 1 year after surgery. In all cases, strength was maintained, and 8 (50%) had continued improvement after Year 1. Ten (63%) returned to their previous employment level. Mean Disabilities of the Arm, Shoulder and Hand score improved from 68 to 83 postoperatively.
Conclusion:
Nerve transfer is a safe, effective technique for correcting penetrating trauma-related nerve injury. In appropriate patients it offers advantages over other techniques. Outcomes can be maintained long term, and many patients can return to their previous level of function.
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