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Related Experiment Video

Updated: Feb 11, 2026

A Fish-feeding Laboratory Bioassay to Assess the Antipredatory Activity of Secondary Metabolites from the Tissues of Marine Organisms

A Fish-feeding Laboratory Bioassay to Assess the Antipredatory Activity of Secondary Metabolites from the Tissues of Marine Organisms

Published on: January 11, 2015

Antibacterial macro molecules from marine organisms.

S Nalini¹, D Sandy Richard¹, S U Mohammed Riyaz¹

¹Centre for Ocean Research, Col. Dr. Jeppiaar Research Park, Sathyabama Institute of Science and Technology, Chennai 600119, India.

International Journal of Biological Macromolecules

|April 28, 2018

Summary

Marine organisms offer a vast, underexplored reservoir of unique antibacterial compounds. This review highlights marine natural products as a promising frontier for developing novel antimicrobial drugs against resistant pathogens.

Keywords:

Antibacterial compound Drug discovery Drug resistant pathogens Marine macromolecules

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Area of Science:

Marine biology and natural product chemistry.
Exploration of marine ecosystems for bioactive compounds.

Background:

Marine ecosystems harbor diverse microorganisms, plants, and animals.
These organisms produce structurally unique antimicrobial macromolecules like peptides, terpenes, alkaloids, and proteins.
Marine natural products represent a promising source for novel antibacterial agents.

Purpose of the Study:

To review antibacterial natural macromolecules derived from various marine sources.
To highlight their potential in drug discovery and biomedical research.
To discuss the mode of action of these marine-derived antibacterial agents.

Main Methods:

Literature review of scientific publications on marine natural products with antibacterial activity.
Compilation of data on identified marine macromolecules and their sources.
Analysis of reported modes of action for antibacterial marine compounds.

Main Results:

Over 30,000 natural macromolecules have been identified from marine organisms.
Marine bacteria, fungi, sponges, algae, and other invertebrates are significant sources.
Many identified compounds show potent activity against drug-resistant pathogenic microorganisms.

Conclusions:

Marine natural macromolecules are a valuable resource for discovering new antibacterial drugs.
Further exploration and validation of these compounds are crucial for combating antimicrobial resistance.
Understanding their mechanisms of action will aid in developing effective therapeutics.