Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

1.2K
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1.2K
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

6.2K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
6.2K
The Extracellular Matrix01:42

The Extracellular Matrix

89.4K
Overview
89.4K
The Placebo Effect01:54

The Placebo Effect

6.9K
The placebo effect occurs when people's expectations or beliefs influence or determine their experience in a given situation. In other words, simply expecting something to happen can actually make it happen.
6.9K
Embryonic Stem Cells00:58

Embryonic Stem Cells

32.6K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
32.6K
Threats to Biodiversity01:50

Threats to Biodiversity

27.2K
There have been five major extinction events throughout geological history, resulting in the elimination of biodiversity, followed by a rebound of species that adapted to the new conditions. In the current geological epoch, the Holocene, there is a sixth extinction event in progress. This mass extinction has been attributed to human activities and is thus provisionally called the Anthropocene. In 2019 the human population reached 7.7 billion people and is projected to comprise 10 billion by...
27.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pulmonary Exposure to Copper Oxide Nanoparticles Induces Systemic Inflammation, Oxidative Stress, and Prothrombotic Responses in BALB/c Mice.

International journal of nanomedicine·2026
Same author

Experiences of Patients With Chronic Kidney Disease Undergoing Hemodialysis: A Qualitative Study in Bangladesh.

Canadian journal of kidney health and disease·2026
Same author

Perspectives on Analytical Treatment Interruptions and Prospects of an HIV Cure Amongst People Living with HIV and Healthcare Providers in Singapore.

AIDS and behavior·2026
Same author

Digital Overload and Connection Demands: Emerging Mental Health Risks for University Students in Low- and Middle-Income Countries.

The International journal of social psychiatry·2026
Same author

Water Added Probiotics Attenuates Sumithion-Induced Toxicity on Growth, Intestinal Deformities, Erythrocytic Abnormalities, and Immunity in Nile Tilapia (<i>Oreochromis niloticus</i>).

Aquaculture nutrition·2026
Same author

Porphyrin-based nanotechnology: a minimally invasive approach for drug delivery and cholesteatoma treatment.

Frontiers in surgery·2025

Related Experiment Video

Updated: Feb 11, 2026

Neonatal Cardiac Scaffolds: Novel Matrices for Regenerative Studies
08:16

Neonatal Cardiac Scaffolds: Novel Matrices for Regenerative Studies

Published on: November 5, 2016

8.2K

Decellularized matrices in regenerative medicine.

Doris A Taylor1, Luiz C Sampaio2, Zannatul Ferdous2

  • 1Center for Cell and Organ Biotechnology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA; Regenerative Medicine Research, Texas Heart Institute, Houston, TX 77225, USA.

Acta Biomaterialia
|April 28, 2018
PubMed
Summary
This summary is machine-generated.

Decellularized extracellular matrix (dECM) offers a natural scaffold for tissue engineering and regenerative medicine. Its unique architecture and composition support cell homing and differentiation, showing promise for clinical applications.

Keywords:
Biological scaffoldDecellularizationExtracellular matrixTissue engineering

More Related Videos

Novel Process for 3D Printing Decellularized Matrices
08:14

Novel Process for 3D Printing Decellularized Matrices

Published on: January 7, 2019

7.6K
Preparation of 3D Decellularized Matrices from Fetal Mouse Skeletal Muscle for Cell Culture
07:44

Preparation of 3D Decellularized Matrices from Fetal Mouse Skeletal Muscle for Cell Culture

Published on: March 3, 2023

1.8K

Related Experiment Videos

Last Updated: Feb 11, 2026

Neonatal Cardiac Scaffolds: Novel Matrices for Regenerative Studies
08:16

Neonatal Cardiac Scaffolds: Novel Matrices for Regenerative Studies

Published on: November 5, 2016

8.2K
Novel Process for 3D Printing Decellularized Matrices
08:14

Novel Process for 3D Printing Decellularized Matrices

Published on: January 7, 2019

7.6K
Preparation of 3D Decellularized Matrices from Fetal Mouse Skeletal Muscle for Cell Culture
07:44

Preparation of 3D Decellularized Matrices from Fetal Mouse Skeletal Muscle for Cell Culture

Published on: March 3, 2023

1.8K

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Decellularized extracellular matrix (dECM) is a promising biologic scaffold.
  • dECM provides a native cellular environment with unique composition and architecture.
  • It can be obtained from various organs and species.

Purpose of the Study:

  • To review the macro- and micro-architecture of dECM.
  • To describe methods for harnessing dECM characteristics for tissue repair.
  • To overview the clinical use and challenges of dECM.

Main Methods:

  • Review of existing literature on dECM.
  • Analysis of dECM's structural and compositional properties.
  • Examination of preclinical and clinical studies.

Main Results:

  • dECM mimics natural tissue environments, offering superior architecture and composition.
  • The decellularization process preserves structural integrity and vasculature.
  • dECM can induce cell differentiation and maturation, supporting tissue regeneration.

Conclusions:

  • dECM is a highly promising scaffold for tissue engineering and regenerative medicine.
  • Addressing challenges in clinical translation is crucial for robust use of dECM.
  • dECM has the potential to become the gold standard for regenerative scaffolds.