Undifferentiated Embryonal Sarcoma of the Liver (UESL) in Adolescents: An Unexpected Diagnosis
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Updated: Feb 11, 2026

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Published on: July 21, 2023
Michele A Capozza1, Antonio Ruggiero1, Palma Maurizi1
1Division of Pediatric Oncology, Catholic University of Rome, A. Gemelli Hospital.
Abstract:
Definitive diagnosis of pediatric liver masses can be challenging, because clinical manifestations are nonspecific, and ultimate diagnosis may be delayed. We describe 2 patients with liver masses that initially were misdiagnosed and treated as infectious hepatic lesions. Only after histologic examination the correct diagnosis of undifferentiated embryonal sarcoma of the liver was defined. Both patients underwent a complete tumor resection followed by chemotherapy with a favorable outcome.
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