Constrictive pericarditis: retrospective study of 109 patients
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Published on: October 25, 2024
Mukesh Kumawat1, Tapan Kumar Lahiri1, Damyanti Agarwal1
1Department of Cardiothoracic and Vascular Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Insights
Chronic constrictive pericarditis, a common diastolic heart disorder, can be effectively treated with pericardiectomy. This surgical procedure, performed via sternotomy or thoracotomy, offers significant improvement in cardiac function.
Area of Science:
- Cardiology
- Cardiac Surgery
- Pericardial Diseases
Background:
- Chronic constrictive pericarditis is the most frequent diastolic heart disorder, characterized by pericardial non-elasticity and impaired diastolic function.
- Clinical presentation often mimics right heart failure, with etiology being historically relevant but not definitively diagnostic.
- Echocardiography and hemodynamic studies are key diagnostic modalities, with pericardial thickness ≥7 mm being highly specific for constrictive features.
Purpose of the Study:
- To evaluate the efficacy and outcomes of pericardiectomy in patients with chronic constrictive pericarditis.
- To compare the outcomes of pericardiectomy performed via different surgical approaches.
Main Methods:
- Retrospective review of data from 109 patients who underwent pericardiectomy between January 1987 and June 2016.
- Analysis of patient outcomes, including mortality and hemodynamic improvement post-surgery.
Main Results:
- The study included 109 patients who underwent pericardiectomy, with a low mortality rate of only 2 patients.
- Pericardiectomy, regardless of surgical approach (mid-sternotomy or anterolateral thoracotomy), demonstrated positive outcomes.
Conclusions:
- Pericardiectomy is a viable treatment for progressive, fibrotic, and thickened pericardial conditions impairing diastolic filling.
- While initial results may not be dramatic, continued improvement is expected due to left ventricular dimension enlargement post-surgery.
Abstract:
Background Chronic constrictive pericarditis is the most common diastolic disorder of the heart. Non-elasticity of the pericardium with impaired cardiac diastolic function is constriction. Chronic constrictive pericarditis is the result of scarring and fibrosis in mid and late diastole. The clinical presentation is similar to that of right heart failure. Historically, the etiology is helpful but not diagnostic. Echocardiography and a hemodynamic study are the main diagnostic tools. A thick pericardium of more than 4 mm is not necessarily constrictive, but thickness ≥7 mm is highly specific for constrictive features. Pericardiectomy is usually associated with early normalization of hemodynamics, which can be achieved via a mid-sternotomy or left anterolateral thoracotomy. Methods Data of 109 patients who underwent pericardiectomy from January 1987 to June 2016 were reviewed retrospectively. Results The outcome of our 109 cases consisted of mortality in 2 patients only. Conclusion Progressive, fibrotic, thickened, adherent inflammatory changes in response to various pathologies of the pericardium impairing diastolic filling can be treated by pericardiectomy. Pericardiectomy can be achieved by a mid-sternotomy or anterolateral thoracotomy without any difference in outcome. The initial hemodynamic and clinical result may not always be dramatic but continued improvement is definite because of progressive enlargement of left ventricular dimensions.
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