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Updated: Feb 11, 2026

Calcified Artery Preparation and Processing with Preserved Morphology and RNA for Digital Spatial Profiling
Published on: January 23, 2026
Techniques of Impella removal while preserving arterial access
1University of California, San Diego Sulpizio Cardiovascular Center, United States.
Maintaining arterial access after removing large mechanical circulatory devices (MCD) is difficult. This paper presents two new techniques and reviews literature on arterial access site preservation following Impella removal.
Area of Science:
- Cardiology
- Vascular Surgery
- Medical Device Technology
Background:
- Large caliber mechanical circulatory devices (MCD) are increasingly used for hemodynamic support.
- Arterial access site management after MCD removal presents significant clinical challenges.
- Standardized protocols for arterial access site preservation post-MCD are lacking.
Observation:
- The removal of large-bore arterial access sheaths used for MCDs can lead to complications.
- Hemorrhage and pseudoaneurysm formation are common concerns at the arterial access site.
- Current literature offers limited guidance on optimal techniques for managing these access sites.
Findings:
- Two novel techniques for arterial access site preservation after Impella removal are described.
- The described techniques aim to minimize complications and ensure vascular integrity.
- A comprehensive review of existing literature on post-MCD arterial access management is provided.
Implications:
- The presented techniques may offer improved outcomes for patients requiring large caliber arterial access.
- Enhanced understanding of arterial access site maintenance can guide clinical practice.
- Further research is warranted to validate the efficacy and long-term safety of these novel approaches.
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