Hypersensitivity reactions to intravenous antibiotics in cystic fibrosis
Marie F A Wright1, Andrew Bush2, Siobhan B Carr1
1Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom.
Abstract:
Hypersensitivity reactions to intravenous antibiotics are common in cystic fibrosis (CF). As well as causing immediate morbidity, the need for future avoidance of the causative antibiotic can have a long-term negative impact on CF management. This paper reviews the epidemiology and clinical presentation of hypersensitivity reactions in CF patients, and using an illustrative case describes a rare but severe form of delayed drug reaction for which a high index of suspicion is required.
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