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Published on: February 22, 2019
[CEUS-Diagnostic of malignant liver lesions]
G Negrão de Figueiredo1, K Müller-Peltzer2, J Rübenthaler2
1Klinik und Poliklinik für Radiologie, Interdisziplinäres Ultraschall-Zentrum, Universitätsklinikum der Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, München, Deutschland. Giovanna.Negrao_de_Figueiredo@med.uni-muenchen.de.
Clinical/Methodical Issue:
Cross-sectional modalities or conventional ultrasound are not always able to sufficiently identify and characterize malignant liver lesions.
Standard Radiological Methods:
The evaluation of malignant liver lesions in conventional ultrasound relies on echostructure, shape and borders, but often warrants additional contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) studies.
Methodical Innovations:
Contrast-enhanced ultrasound (CEUS) is a relatively safe imaging technique used for the detection and characterization of malignant liver lesions. The use of a second-generation contrast agent in dynamic real-time imaging allows the visualization of vascularization in any kind of liver lesion as well as liver perfusion during the arterial, portal venous and late phase.
Performance:
Due to the different enhancement patterns, it is possible to differentiate a liver lesion with high diagnostic accuracy (over 90%).
Achievements:
CEUS is a helpful complementary technique to cross-sectional imaging for the evaluation of unclear liver lesions and may frequently obviate additional contrast-enhanced MRI or CT studies.
Practical Recommendations:
CEUS enables the detection and characterization of liver lesions in real time.
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