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Published on: September 13, 2022
Infection following percutaneous vertebral augmentation with polymethylmethacrylate
Jae-Woo Park1, Sang-Min Park2, Hui Jong Lee3
1Department of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Postoperative infection after vertebroplasty or kyphoplasty is rare but can be life-threatening. Prompt diagnosis with culture and biopsy, followed by long-term antibiotics and surgical intervention when needed, is crucial for patient recovery.
Area of Science:
- Spinal surgery
- Infectious disease
Background:
- Vertebral augmentation procedures like vertebroplasty and kyphoplasty carry a rare risk of postoperative infection.
- Infection can lead to severe complications, particularly in elderly patients with comorbidities.
Purpose of the Study:
- To analyze 11 cases of pyogenic spondylitis and spondylodiscitis following vertebral augmentation.
- To review the literature for similar cases of infection after vertebroplasty or kyphoplasty.
Main Methods:
- Retrospective review of postoperative spinal infections after percutaneous vertebroplasty or kyphoplasty between January 2005 and November 2016.
- Inclusion of 11 patients with a mean age of 76.3 years.
Main Results:
- The incidence of infection was 0.36% (3 of 826 cases).
- All patients received combined surgical and antibiotic treatment.
- Ten out of eleven patients recovered after a mean follow-up of 21.1 months.
Conclusions:
- Postoperative infection following vertebral augmentation is rare but potentially life-threatening, especially in frail patients.
- Immediate culture and biopsy, long-term antibiotics, and prompt surgical intervention are critical for managing these infections.
- Surgical treatment is indicated for significant neurologic deficit, instability, or antibiotic resistance.
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