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Sleep disturbance in psoriasis: a case-controlled study
P Jensen1, C Zachariae1, L Skov1
1Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900, Hellerup, Denmark.
The British Journal of Dermatology
|April 29, 2018
Summary
Patients with psoriasis experience significantly more sleep disturbances than the general population. Itch is the primary predictor of poor sleep, suggesting that managing psoriasis symptoms could improve sleep quality.
Area of Science:
- Dermatology
- Sleep Medicine
- Psychiatry
Background:
- Sleep disturbances are common in patients with psoriasis due to physical symptoms.
- Previous studies on sleep in psoriasis have yielded mixed results and methodological limitations.
Purpose of the Study:
- To determine the prevalence of sleep disturbance in plaque psoriasis patients compared to controls.
- To assess the relationship between sleep disturbance, health-related quality of life (HRQoL), and psoriasis.
- To identify disease-related predictors of disturbed sleep in psoriasis patients.
Main Methods:
- Cross-sectional, case-controlled study design.
- 179 patients with plaque psoriasis and 105 controls were recruited.
- Evaluated psoriasis severity, HRQoL, insomnia severity, sleep quality, stress, itch, and depressive symptoms.
Main Results:
- 25% of psoriasis patients reported clinical insomnia versus 10.5% of controls.
- 53.6% of psoriasis patients were poor sleepers compared to 21.9% of controls.
- Itch severity was significantly associated with all measured sleep outcomes.
Conclusions:
- Patients with psoriasis exhibit a higher prevalence of poor sleep compared to the general population.
- Itch is a key predictor of sleep impairment in psoriasis.
- Effective management of psoriasis and associated itch may alleviate sleep disturbances.
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