Related Experiment Video

Updated: Feb 11, 2026

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
10:01

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation

Published on: July 10, 2012

21.1K

Chronic Cough Related to Acute Viral Bronchiolitis in Children: CHEST Expert Panel Report

Anne B Chang1, John J Oppenheimer2, Bruce K Rubin3

  • 1Division of Child Health, Menzies School of Health Research, Darwin, Australia; Respiratory and Sleep Department, Lady Cilento Children's Hospital, Qld Uni of Technology, Brisbane, QLD, Australia.

Chest
|April 29, 2018
PubMed

Insights

This study found no evidence to recommend antibiotics, asthma medications, or hypertonic saline for treating chronic cough in children after acute viral bronchiolitis. Further research is needed for effective management strategies.

Area of Science:

  • Pediatric Pulmonology
  • Evidence-Based Medicine

Background:

  • Acute bronchiolitis is a common childhood illness.
  • A subset of children experience persistent chronic cough exceeding four weeks post-infection.

Purpose of the Study:

  • To systematically review the efficacy of antibiotics, asthma medications, and inhaled osmotic agents for chronic cough post-bronchiolitis in children.
  • To formulate evidence-based recommendations for managing this condition.

Main Methods:

  • Systematic reviews were conducted using PICO format and CHEST guidelines.
  • GRADE framework and Delphi methodology were employed to reach consensus.
  • Patient values and clinical context were integrated into suggestions.

Main Results:

  • No relevant data were found for the efficacy of antibiotics, asthma medications, or hypertonic saline in addressing chronic cough post-bronchiolitis.
  • Consequently, no recommendations could be formulated for these interventions.

Conclusions:

  • Consensus-based suggestions were developed in the absence of direct evidence.
  • Future research directions were identified to improve the management of chronic cough in children following acute viral bronchiolitis.
Abstract

Keywords:
coughevidence-based medicineguidelines

More Related Videos

Methods for Detecting Cough and Airway Inflammation in Mice04:33

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

1.3K
In vivo Imaging Method to Distinguish Acute and Chronic Inflammation07:10

In vivo Imaging Method to Distinguish Acute and Chronic Inflammation

Published on: August 16, 2013

20.8K

Related Concept Videos

Wood Panel Products01:18

Wood Panel Products

Wood panel products are essential materials used in construction for applications such as flooring, siding, and roofing, typically available in standard dimensions of 4 feet by 8 feet, with thicknesses varying from one-quarter of an inch to one and one-eighth inches. Among the most common types of wood panels is plywood, which is produced by gluing multiple layers of thin wood veneers under pressure. The grain of the outer veneers runs lengthwise, while the grains of the interior layers run...
408
Flail Chest-I01:24

Flail Chest-I

Overview of Flail Chest
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...
760
Flail Chest-II01:26

Flail Chest-II

Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
656
Chest Physiotherapy01:24

Chest Physiotherapy

Chest Physiotherapy (CPT) is a therapeutic technique used in respiratory care to improve ventilation, clear bronchial secretions, and enhance the efficiency of respiratory muscles. This therapy includes three primary procedures: postural drainage, percussion, and vibration. It can be performed on spontaneously breathing patients and those who are intubated and mechanically ventilated.
Purpose
CPT is primarily used for patients with excessive bronchial secretions who have difficulty clearing...
1.9K
Data Reporting and Recording01:24

Data Reporting and Recording

Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.5K
Viral Recombination00:57

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
25.2K