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Sphingolipid-mediated calcium signaling and its pathological effects

Ilari Pulli1, Muhammad Yasir Asghar2, Kati Kemppainen1

  • 1Cell Biology, Faculty of Science and Engineering, Åbo Akademi University, Artillerigatan 6, 00250 Turku, Finland.

Biochimica Et Biophysica Acta. Molecular Cell Research
|April 29, 2018
PubMed
Summary

Sphingomyelin metabolites, like sphingosine and sphingosine 1-phosphate (S1P), significantly impact cellular signaling by modulating calcium ion fluxes. This review explores these lipid-calcium interactions and their physiological and pathological implications.

Keywords:
CalciumSignaling: receptorsSphingolipidsSphingosine 1-phosphate

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