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Retinoids and acne.

J J Leyden1

  • 1Duhring Laboratories, University of Pennsylvania, Philadelphia 19104.

Journal of the American Academy of Dermatology
|July 1, 1988
PubMed
Summary
This summary is machine-generated.

Retinoids, vitamin A derivatives, are effective treatments for skin conditions like acne. This review covers the historical and current use of various retinoids for acne management.

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Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Retinoids, compounds with vitamin A activity, are crucial in treating skin disorders.
  • Acne vulgaris is a common skin condition with various treatment options.

Purpose of the Study:

  • To review the historical and current applications of retinoids in acne treatment.
  • To discuss different types of retinoids used for managing acne.

Main Methods:

  • Literature review of retinoid use in dermatology.
  • Analysis of historical and contemporary research on retinoids for acne.

Main Results:

  • Retinoids have evolved as key therapeutic agents for cutaneous disorders, notably acne.
  • The review encompasses topical and systemic retinoids, including retinol, tretinoin, isotretinoin, and etretinate.

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  • Investigational retinoid molecules are also considered for future acne therapies.

    • Conclusions:

    • Retinoids represent a significant advancement in acne treatment.
    • The ongoing development of novel retinoid molecules promises further improvements in managing acne vulgaris.