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Does exposure to PM10 decrease age at menarche?
Eun Mi Jung1, Hae Soon Kim2, Hyesook Park3
1Department of Occupational and Environmental Medicine, College of Medicine, Ewha Womans University, Seoul, Republic of Korea; Ewha Global Health Institute for Girls, College of Medicine, Ewha Womans University, Seoul, Republic of Korea.
Environment International
|April 29, 2018
Summary
Exposure to particulate matter (PM10) is linked to earlier age at menarche in South Korean adolescents. This study highlights PM10 as a significant environmental factor influencing reproductive development.
Area of Science:
- Environmental Health
- Reproductive Epidemiology
- Public Health
Background:
- A consistent decrease in the age of menarche has been observed in South Korea.
- Exposure to endocrine-disrupting compounds in particulate matter (PM) is a potential risk factor for early menarche.
Purpose of the Study:
- To investigate the association between pre-menarcheal exposure to PM10 and age at menarche.
- Utilized data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2010-2012.
Main Methods:
- Analyzed self-reported menarche age of 639 girls (aged 13-17).
- Linked 1-year, 2-year, and 3-year averages of annual mean PM10 concentrations to participant addresses.
- Adjusted for BMI, city size, income, maternal age at menarche, and secondhand smoke exposure.
Main Results:
- Elevated PM10 exposure significantly decreased age at menarche.
- Each 1 μg/m³ increase in PM10 accelerated menarche by 0.031-0.046 years.
- Increased PM10 concentration was associated with higher odds of earlier menarche (ORs 1.05-1.08).
Conclusions:
- Elevated PM10 concentration is associated with a decrease in age at menarche.
- This is the first study on PM10 and age at menarche using a nationally representative Korean sample.
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