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Testosterone and sexual function in men.

Giulia Rastrelli1, Giovanni Corona2, Mario Maggi3

  • 1Sexual Medicine and Andrology Unit Department of Experimental Clinical and Biomedical Sciences "Mario Serio", University of Florence, Viale Pieraccini, 6, 50139 Florence, Italy.

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Summary
This summary is machine-generated.

Testosterone therapy improves sexual function, but only in men with confirmed hypogonadism and specific sexual disorders. Other factors often cause sexual dysfunction, and treatment should address these alongside testosterone levels.

Keywords:
Delayed ejaculationErectile dysfunctionSexual desireTestosteroneTestosterone treatment

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Area of Science:

  • Endocrinology
  • Men's Health
  • Sexual Medicine

Background:

  • Testosterone (T) plays a crucial role in male sexual response.
  • Sexual disorders are not solely caused by low T levels; organic, relational, and psychological factors are significant.
  • Erectile dysfunction (ED) can stem from vascular issues or low T.

Purpose of the Study:

  • To clarify the complex relationship between testosterone levels and male sexual function.
  • To determine the efficacy of testosterone therapy (TTh) in treating various sexual dysfunctions.
  • To emphasize the multifactorial nature of sexual disorders.

Main Methods:

  • Review of meta-analyses and clinical recognition of factors influencing sexual function.
  • Analysis of TTh effectiveness based on patient hypogonadism status.
  • Emphasis on the necessity of assessing serum T levels and other conditions before TTh.

Main Results:

  • TTh improves erectile function only in men with ED and overt hypogonadism.
  • Low sexual desire is often linked to hypogonadism and improves with TTh in these cases.
  • TTh may improve orgasmic function in hypogonadal men; its role in delayed ejaculation requires further study.

Conclusions:

  • Sexual dysfunctions are multifactorial; hypogonadism is only one potential cause.
  • Testosterone therapy is most effective for sexual symptoms in men with confirmed hypogonadism.
  • Prior to prescribing TTh, assessing serum T levels and other coexisting conditions is mandatory.