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Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels
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1000 consecutive liver transplants. Descriptive analysis and evolution of a single center
José Tinoco González1, Jose María Álamo Martínez1, Carmen Bernal Bellido1
1Unidad de Cirugía Hepatobiliopancreática y Trasplante Hepático, Hospital Universitario Virgen del Rocío, Sevilla, España.
Abstract:
Between 1991 and 2013, 1,000 liver transplantations were performed at Virgen del Rocio Hospital (Seville, Spain). A retrospective study was conducted, analyzing the characteristics of recipients and donors, indications, surgical technique, complications and survival in 2 different stages (1991-2002 vs. 2003-2013) coinciding with the implementation of the MELD scale as a prioritization model. The most frequent indication were of hepatopathy of hepatocellular origin in 48.8%. There was a significant increase in the indications for hepatocarcinoma (8.6% and 24.1% P=0.03), and the rate of retransplantation (5.9% vs 9.6%, P=0.04). There was a change in the age of donation, going from 27.7 years in 1990 to 62.9 years in 2012 (P=0.001). The percentage of patients who did not require blood transfusion doubled (6.16 vs. 14.31%, P=.001). Survival of all patients after one, 5 and 10 years was 77, 63.5 and 51.3%, respectively.
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