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The Timing of Initiating Complementary Feeding in Preterm Infants and Its Effect on Overweight: A Systematic Review
Karin M Vissers1, Edith J M Feskens2, Johannes B van Goudoever3
1Department of Pediatrics, Hospital Gelderse Vallei, Ede, the Netherlands.
Insights
The optimal timing for starting complementary feeding in preterm infants remains unclear. Current research shows no significant impact on body mass index (BMI) Z-scores, but more studies are needed to understand long-term effects on overweight risk.
Area of Science:
- Pediatrics
- Neonatology
- Nutrition Science
Background:
- The appropriate timing for initiating complementary feeding in preterm infants is a subject of ongoing debate.
- Existing research suggests a potential link between complementary feeding timing and overweight development in term infants.
Purpose of the Study:
- To systematically review the effect of complementary feeding initiation timing on overweight outcomes in preterm infants.
Main Methods:
- A systematic literature search was conducted using terms related to preterm infants, complementary feeding, and overweight.
- Five studies, including three randomized controlled trials and two cohort studies, were included in the review.
Main Results:
- Two randomized controlled trials found no significant difference in body mass index (BMI) Z-scores at 12 months.
- One randomized controlled trial indicated a greater growth rate in infants weaned earlier.
- One observational study suggested delayed complementary feeding was associated with reduced length and weight Z-scores.
Conclusions:
- No definitive conclusion could be drawn regarding the effect of complementary feeding timing on overweight in preterm infants.
- Further research is necessary to clarify the impact of complementary feeding initiation timing on overweight in this population.
Background:
What is the appropriate time to start complementary feeding for preterm infants? The answer to this question is yet under debate. The timing of initiating complementary feeding may be associated with overweight in term infants. This systematic review aimed to study the effect of the timing of initiating complementary feeding on overweight in preterm infants. Predefined search items included preterm infants, complementary feeding, overweight, and their synonyms.
Summary:
The search identified 15,749 articles, of which 5 articles were included. Three studies presented data of randomized controlled trials and 2 studies were cohort studies. Two randomized controlled trials found no significant difference in body mass index (BMI) Z-score between the intervention groups at 12 months of age. One randomized controlled trial presented a significant greater mean rate of growth in length per week until 12 months in the preterm weaning strategy-group compared with the current best practices. One observational study concluded that each month the infants received complementary food later, the Z-score for length and weight was reduced by 0.1. Key Messages: No clear conclusion could be drawn from the included studies. This review illustrates the need for further research to access the effect of the timing of initiating complementary feeding on overweight in preterm infants.
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