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Updated: Feb 11, 2026

Perturbing Endothelial Biomechanics via Connexin 43 Structural Disruption
Published on: October 4, 2019
[Correlation of connexin 43 with testicular tumors]
1Department of Pharmacy, Zhangjiagang First People's Hospital, Zhangjiagang, Jiangsu 215600, China .
Abstract:
Gap junctions (GJ), as a special membrane structure between adjacent cells, are composed of connexins (Cx) and regulate the proliferation and differentiation of cells. Studies show that gap junctional intercellular communication is weakened or lost in most tumor cells and this abnormality is often accompanied by changed expression of Cxs. Cx43 is a major connexin in the testis tissue. This review focuses on the latest progress in the studies of Cx43 in testicular tumors.
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