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Updated: Feb 11, 2026

Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus
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Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus

Published on: October 14, 2022

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Ventriculoperitoneal shunt infections and re-infections in children: a multicentre retrospective study

Nurhayat Yakut1, Ahmet Soysal1, Eda Kepenekli Kadayifci1

  • 1a Marmara University School of Medicine , Istanbul , Turkey.

British Journal of Neurosurgery
|May 1, 2018
PubMed

Insights

Ventriculoperitoneal shunt (VPS) infections in children are common, with coagulase-negative staphylococci being the most frequent pathogen. High cerebrospinal fluid (CSF) protein levels before shunt re-insertion may increase the risk of re-infection.

Area of Science:

  • Pediatric Neurosurgery
  • Infectious Diseases
  • Medical Device Complications

Background:

  • Ventriculoperitoneal shunts (VPS) are standard treatment for hydrocephalus.
  • VPS infections are serious complications, leading to high mortality and morbidity.
  • Identifying causative agents and risk factors for re-infection is crucial for pediatric patients.

Purpose of the Study:

  • Investigate the causative agents of VPS infections in children.
  • Analyze the management strategies for VPS infections.
  • Identify risk factors associated with VPS re-infection in pediatric cases.

Main Methods:

  • Retrospective, multicentre study conducted in Turkey.
  • Involved pediatric and neurosurgery departments across four tertiary medical centers.
  • Data collected from January 2011 to September 2014.

Main Results:

  • 290 patients with VPS infections were identified.
  • Coagulase-negative staphylococci were the most common pathogen (42.5%), followed by Pseudomonas aeruginosa.
  • Elevated CSF protein levels (>100 mg/dL) prior to VPS insertion were linked to a higher risk of re-infection (OR, 1.65; p=.01).

Conclusions:

  • High pre-insertion CSF protein levels (>100 mg/dL) may indicate an increased risk for VPS re-infection.
  • Prompt identification and management of causative agents are essential.
  • Further research into preventative strategies for VPS infections is warranted.
Abstract

Keywords:
Ventriculoperitoneal shunt infectionchildrenre-infectionrisk factors

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