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Updated: Feb 11, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Recurrent Acute Ischemic Stroke after Infective Endocarditis Caused by Streptococcus Constellatus: First Case Report
Yumin Wang1, Weili Zhao2, Jun Lu2
1Department of Oncology, The Affiliated Hospital of Chifeng University, Chifeng, China.
Insights
Infective endocarditis (IE) can cause recurrent acute ischemic strokes (AIS), even without visible vegetations. This case highlights Streptococcus constellatus IE as a rare cause of concurrent anterior and posterior circulation infarcts.
Area of Science:
- Cardiology
- Neurology
- Infectious Diseases
Background:
- Acute ischemic stroke (AIS) is a frequent complication of infective endocarditis (IE).
- Recurrent strokes involving multiple circulation patterns due to IE are rarely documented.
- Identifying IE as a cause of AIS is crucial for timely treatment and improved outcomes.
Abstract:
Acute ischemic stroke (AIS) is highly prevalent in patients with infective endocarditis (IE) and associated with high rates of death and disability. IE presenting as an acute ischemic stroke, especially recurrent concurrence of acute anterior and posterior circulation infarct, has rarely been reported. Herein, we report a case study of a 60-year-old man with a history of aortic valve replacement and was under warfarin, presented with recurrent acute ischemic stroke which was found to have no vegetation secondary to infective endocarditis caused by Streptococcus constellatus as the embolic source. This is the first case report of recurrent ischemic stroke secondary to IE without vegetation caused by Streptococcus constellatus involving concurrence of acute anterior and posterior circulation. We also then systematically analyze the cases with IE initially presenting as AIS reported in the literature to establish possible demographic, clinical, laboratory patterns, and prognostic features of these cases.
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