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Author Spotlight: Advancing Cardiac Procedure Testing Prior to Embarking on Large Animal Studies
Published on: August 25, 2023
Novel diffuse optics system for continuous tissue viability monitoring - extended recovery in vivo testing in a
Seung Yup Lee1, Julia M Pakela2, Taylor L Hedrick1
1Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109.
Abstract:
In reconstructive surgery, tissue perfusion/vessel patency is critical to the success of microvascular free tissue flaps. Early detection of flap failure secondary to compromise of vascular perfusion would significantly increase the chances of flap salvage. We have developed a compact, clinically-compatible monitoring system to enable automated, minimally-invasive, continuous, and quantitative assessment of flap viability/perfusion. We tested the system's continuous monitoring capability during extended non-recovery surgery using an in vivo porcine free flap model. Initial results indicated that the system could assess flap viability/perfusion in a quantitative and continuous manner. With proven performance, the compact form constructed with cost-effective components would make this system suitable for clinical translation.
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