Related Experiment Video
Updated: Feb 11, 2026
Instillation and Fixation Methods Useful in Mouse Lung Cancer Research
Published on: August 31, 2015
Reduced Lung Cancer Mortality With Lower Atmospheric Pressure
1Department of Health Science, College of Life Sciences, Brigham Young University, Provo, UT, USA.
Background:
Research has shown that higher altitude is associated with lower risk of lung cancer and improved survival among patients. The current study assessed the influence of county-level atmospheric pressure (a measure reflecting both altitude and temperature) on age-adjusted lung cancer mortality rates in the contiguous United States, with 2 forms of spatial regression.
Methods:
Ordinary least squares regression and geographically weighted regression models were used to evaluate the impact of climate and other selected variables on lung cancer mortality, based on 2974 counties.
Results:
Atmospheric pressure was significantly positively associated with lung cancer mortality, after controlling for sunlight, precipitation, PM2.5 (µg/m3), current smoker, and other selected variables. Positive county-level β coefficient estimates (P < .05) for atmospheric pressure were observed throughout the United States, higher in the eastern half of the country.
Conclusion:
The spatial regression models showed that atmospheric pressure is positively associated with age-adjusted lung cancer mortality rates, after controlling for other selected variables.
Related Concept Videos
02:57Definition and Measurement of Pressure: Atmospheric Pressure, Barometer, and Manometer
01:18Variation of Atmospheric Pressure
Assuming the air temperature is constant at a given altitude and that the ideal gas law of thermodynamics describes the atmosphere to a good approximation, one can find the variation of atmospheric pressure with height.
Let p(y) be the atmospheric pressure at...
02:34Vapor Pressure
03:02Constant Pressure Calorimetry
01:47Lung Capacity
02:40Osmosis and Osmotic Pressure of Solutions