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Suspected Blood Indicator to Identify Active Gastrointestinal Bleeding: A Prospective Validation
Samuel Han1, Julien Fahed1, David R Cave1
1Division of Gastroenterology, University of Massachusetts Medical Center, Worcester, MA, USA.
Gastroenterology Research
|May 1, 2018
Summary
The Suspected Blood Indicator (SBI) function in video capsule endoscopy accurately detects active gastrointestinal bleeding. A refined algorithm using eight contiguous SBI markers achieved 100% sensitivity and specificity.
Area of Science:
- Gastroenterology
- Medical Imaging
- Endoscopy
Background:
- The Suspected Blood Indicator (SBI) function in RAPID Reader v8.3 aids blood detection in video capsule endoscopy (VCE).
- Previous studies indicated SBI's accuracy in detecting small bowel bleeding but noted poor specificity and sensitivity.
Purpose of the Study:
- To develop and validate a highly accurate algorithm for identifying active gastrointestinal bleeding using the SBI function in VCE.
- To improve the diagnostic performance of the SBI function for active bleeding detection.
Main Methods:
- Phase 1: A retrospective review of 115 patients with active bleeding and 115 without active bleeding on VCE to create an algorithm.
- Phase 2: A prospective study applying the developed algorithm to 100 consecutive VCE patients for various bleeding indications.
Main Results:
- The retrospective review identified eight contiguous SBI markers as highly specific (100%) for active gastrointestinal bleeding.
- The prospective study, using eight contiguous SBI markers as a cutoff, demonstrated 100% sensitivity and specificity for detecting active gastrointestinal bleeding (P < 0.001).
Conclusions:
- The refined SBI function algorithm, utilizing eight contiguous SBI markers, significantly enhances the identification of active gastrointestinal bleeding on VCE.
- This approach offers a reliable and precise method for diagnosing active bleeding during endoscopic procedures.
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