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Cutaneous lymphosarcoma of helper/inducer T-cell origin in a calf
R D Zwahlen1, A Tontis, A Schneider
1Institute of Veterinary Pathology and Large Animal Clinic, Veterinary School, University of Berne, Switzerland.
Veterinary Pathology
|November 1, 1987
Abstract:
A calf with a lymphoproliferative disease resembling human mycosis fungoides, had multiple, ulcerated skin nodules with enlarged regional lymph nodes. Tumor cells were 10-15 micron in diameter and had round to oval nuclei without indentations. Mitoses were regularly present. Pautrier's microabscesses were in the epidermis, and T-cell areas of regional lymph nodes were infiltrated by neoplastic cells. Demonstration of the T-helper/inducer origin of neoplastic lymphocytes suggested classification in analogy with human mycosis fungoides.