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Peak expiratory flow among healthy children aged 5-14 years in China

Yanhong Lu1, Jinping Zheng2, Chuanhe Liu3

  • 1Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou 215003, China.

Journal of Thoracic Disease
|May 1, 2018
PubMed

Insights

This study established normal peak expiratory flow (PEF) values and predictive equations for Chinese children aged 5-14 years. These findings provide essential data for asthma management in this population.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Physiology

Background:

  • Global Initiative for Asthma guidelines recommend peak expiratory flow (PEF) for asthma assessment.
  • Normal PEF values for Chinese children are not well-established.
  • Accurate PEF reference values are crucial for effective asthma management.

Purpose of the Study:

  • To establish normal peak expiratory flow (PEF) reference values for healthy Chinese children aged 5-14 years.
  • To develop predictive equations for PEF based on height for Chinese children.
  • To compare established PEF values with international references.

Main Methods:

  • A cross-sectional study involving 3,169 healthy children aged 5-14 years from five Chinese cities.
  • Pediatric reference values for PEF were established using a mini peak flow meter.
  • PEF measurements from the mini peak flow meter were compared with spirometer data.

Main Results:

  • Height showed the strongest correlation with PEF in both sexes.
  • Significant differences in PEF were observed between males and females.
  • Developed regression equations: Boys: PEF = 4.39 × height (cm) - 300.48; Girls: PEF = 4.13 × height (cm) - 278.04.
  • PEF values by age were similar to Irish, Turkish, and British children, but lower than Greek.
  • PEF values by height were similar to Turkish and Danish children, but lower than Irish.

Conclusions:

  • Normal PEF values and predictive equations were established for Chinese children aged 5-14 years.
  • Existing references from Greece and Ireland are not appropriate for Chinese children.
  • These findings support improved asthma diagnosis and management in Chinese children.
Abstract

Keywords:
Peak expiratory flow (PEF)childrenforced expiratory volume in 1 second (FEV1)

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