Related Experiment Video
Updated: Feb 11, 2026

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
Multispectral photoacoustic microscopy and optical coherence tomography using a single supercontinuum source
M Bondu1,2, M J Marques1, P M Moselund2
1University of Kent, Applied Optics Group, School of Physical Sciences, Ingram building, Canterbury CT2 7NH, United Kingdom.
Abstract:
We report on the use of a single supercontinuum (SC) source for multimodal imaging. The 2-octave bandwidth (475-2300 nm) makes the SC source suitable for optical coherence tomography (OCT) as well as for multispectral photoacoustic microscopy (MPAM). The IR band centered at 1310 nm is chosen for OCT to penetrate deeper into tissue with 8 mW average power on the sample. The 500-840 nm band is used for MPAM. The source has the ability to select the central wavelength as well as the spectral bandwidth. An energy of more than 35 nJ within a less than 50 nm bandwidth is achieved on the sample for wavelengths longer than 500 nm. In the present paper, we demonstrate the capabilities of such a multimodality imaging instrument based on a single optical source. In vitro mouse ear B-scan images are presented.
Related Concept Videos
Imaging Biological Samples with Optical Microscopy
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Electron Microscope Tomography and Single-particle Reconstruction
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Sinusoidal Sources
In homes, the power supplies use sinusoidal sources to provide electricity. These sources generate a voltage that varies sinusoidally...
AC Sources
Sources of Law
Constitutional law is foundational, deriving from federal and state constitutions, and...
Source Transformation
It is essential to note that when...

