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Author Spotlight: High-Throughput Measurement of Intracellular ROS Levels in Hepatocellular Lines
Published on: January 19, 2024
Defining ROS in Biology and Medicine
Robert Li1,2,3,4, Zhenquan Jia4, Michael A Trush5
1Departments of Pharmacology and Pharmaceutical Sciences, Campbell University, Buies Creek, NC 27506, USA.
Abstract:
Utilization of molecular oxygen by aerobic organisms inevitably results in the formation of a number of oxygen-containing reactive species that are collectively known as reactive oxygen species (ROS). ROS play important roles in both physiology and pathophysiology of aerobic life. The field of 'ROS biology and medicine' deals with the involvement of ROS and related species in contemporary biology and medicine. The purpose of this article is to survey common terms and concepts in ROS biology and medicine. It also introduces the 'ROS paradigm' so as to provide a conceptual framework for understanding the rapidly evolving field of ROS biology and medicine.
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