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Multiple sclerosis management and reproductive changes: A guide for general neurologists.
Marwa Kaisey1, Nancy Sicotte1, Barbara Giesser1
1Department of Neurology (MK, MS), Cedars-Sinai Medical Center, Los Angeles, CA; and Department of Neurology (BG), University of California, Los Angeles.
Neurology. Clinical Practice
|May 1, 2018
Summary
This review guides neurologists on managing multiple sclerosis (MS) in women across reproductive stages. With proper planning, pregnancy is safe for women with MS, adapting care for fertility, pregnancy, and menopause.
Area of Science:
- Neurology
- Reproductive Health
- Women's Health
Background:
- Multiple sclerosis (MS) activity and symptoms are influenced by hormonal fluctuations.
- Reproductive health variables are increasingly recognized for their impact on MS risk and exacerbation.
Purpose of the Study:
- To provide a practical guide for neurologists on the standard of care for women with MS throughout their reproductive life.
- To address common patient questions regarding MS management, fertility, pregnancy, and menopause.
Main Methods:
- Literature review of current standards of care.
- Synthesis of evidence from clinical trials and expert opinion.
Main Results:
- Recent research highlights the connection between reproductive health and MS.
- Management strategies for disease-modifying therapies during prenatal and postnatal periods are a key focus.
Conclusions:
- Multiple sclerosis management requires adaptation across a woman's reproductive lifespan.
- Pregnancy is achievable and safe for women with MS through careful planning and management.
- This review serves as a concise resource for neurologists caring for women with MS.
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