Unstable haemoglobin variant Hb Leiden is detected on Sysmex XN-Series analysers

Histone variants are the histone proteins with structural and sequence variations. These variants may be regarded as “mutant” forms that replace their canonical histone counterparts in the nucleosomes. Specific post-translational modifications on the histone variants enable further chromatin complexity and regulate tissue-specific gene expression. The most common histone variants are from histone H2A, H2B, and linker histone H1 families. However, several variants of histone H3...

A resistor is an ohmic device that limits the flow of charge in a circuit. Most circuits have more than one resistor. If several resistors are connected together and connected to a battery, the current supplied by the battery depends on the equivalent resistance of the circuit. The equivalent resistance of a combination of resistors depends on both their individual values and how they are connected. The simplest combination of resistors is the series combination. 
In a series circuit, the...

The RLC circuit impedance is defined as the ratio of the supply voltage to the circuit current. Resonance in such a circuit occurs when the imaginary part of this impedance equals zero. This specific condition means that the inductive reactance is exactly equal to the capacitive reactance. The frequency at which this happens is known as the resonant frequency. Mathematically, the resonant frequency is inversely proportional to the square root of the product of the inductance (L) and capacitance...

Capacitors, fundamental components in electronic circuits, can be connected in series and/or parallel configurations. Each configuration has different impacts on the overall behavior of the circuit.
First, consider capacitors connected in series to a battery. In this configuration, the plate connected to the battery's positive terminal develops a positive charge, while the plate attached to the negative terminal becomes negatively charged. An equal magnitude of charge is induced on the...

Fourier series is a foundational mathematical technique that decomposes periodic functions into an infinite series of sinusoidal harmonics. This method enables the representation of complex periodic signals as sums of simple sine and cosine functions, facilitating their analysis and interpretation in various fields, including signal processing, acoustics, and electrical engineering.
The trigonometric Fourier series specifically expresses a periodic function with a defined period T using sine...

The Fourier series is a powerful mathematical tool for representing periodic signals as an infinite sum of complex exponentials. In practice, this infinite series is truncated to a finite number of terms, yielding a partial sum. This truncation makes the approximation of the signal feasible but introduces certain challenges, particularly near discontinuities, known as the Gibbs phenomenon.
The Gibbs phenomenon refers to the persistent oscillations and overshoots that occur near discontinuities...