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Related Concept Videos

Overview of Advanced Functional Groups02:22

Overview of Advanced Functional Groups

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Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
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Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
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Related Experiment Video

Updated: Feb 11, 2026

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
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Recent advances in wavefront-guided LASIK.

Edward Manche1, Joshua Roe

  • 1The Byers Eye Institute, Stanford University School of Medicine, Palo Alto, California, USA.

Current Opinion in Ophthalmology
|May 1, 2018
PubMed
Summary

Recent advancements in wavefront-guided laser in-situ keratomileusis (LASIK) have improved refractive error correction. This laser vision correction method shows a trend toward superiority, though further comparative studies are needed.

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Area of Science:

  • Ophthalmology
  • Refractive Surgery
  • Laser Vision Correction

Background:

  • Laser vision correction is a dynamic field with ongoing research and development.
  • Wavefront-guided laser in-situ keratomileusis (LASIK) is a prevalent method for vision correction.

Purpose of the Study:

  • To review recent advancements in wavefront-guided LASIK.
  • To update on the latest technological improvements in this laser vision correction technique.

Main Methods:

  • Review of recent technological advancements in wavefront aberrometry.
  • Evaluation of improvements in femtosecond and excimer laser technology for corneal ablation and flap creation.

Main Results:

  • Technological advancements in wavefront aberrometry have led to improved visual outcomes.
  • Femtosecond and excimer lasers show superior results compared to older technologies.
  • Wavefront-guided LASIK demonstrates advantages in visual acuity, predictability, astigmatism correction, and subjective visual symptoms.

Conclusions:

  • Improvements in wavefront aberrometry and laser technology enhance refractive error correction.
  • Wavefront-guided LASIK is an effective and well-tolerated procedure with a trend toward superiority.
  • Further comparative studies are necessary to define the optimal role of wavefront-guided LASIK among keratorefractive modalities.