Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

What is Evolutionary History?

What is Evolutionary History?

Scientists record evolutionary history by analyzing fossil, morphological, and genetic data. The fossil record documents the history of life on Earth and provides evidence for evolution. However, both fossil and living organisms offer evidence that outlines Earth’s evolutionary history.

Evolutionary Psychology

Evolutionary Psychology

Evolutionary psychology explores the origins of human behavior and mental processes by framing them within the context of natural selection, a theory famously propounded by Charles Darwin. This field asserts that many behaviors common across human societies — ranging from instinctive fear reactions to complex social interactions — arose as evolutionary adaptations. These adaptations enhanced the survival and reproductive success of our ancestors, thereby becoming embedded in the...

Criticisms of the Evolutionary Perspective

Criticisms of the Evolutionary Perspective

In a study where individuals posing as strangers offered compliments and proposed casual sex to students, the responses differed significantly based on gender. Not a single woman accepted the proposal, while 70% of the men agreed. This outcome provides a useful scenario to explore through the lens of evolutionary psychology and social learning theory, highlighting the diverse perspectives on human sexual behaviors.
Evolutionary psychology provides one explanation for these findings, suggesting...

Noncovalent Attractions in Biomolecules

Noncovalent Attractions in Biomolecules

Noncovalent Attractions in Biomolecules

Noncovalent Attractions in Biomolecules

Noncovalent attractions are associations within and between molecules that influence the shape and structural stability of complexes. These interactions differ from covalent bonding in that they do not involve sharing of electrons.
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...

Evolutionary Relationships through Genome Comparisons

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Genomic Diversity of Aurochs From a Mediterranean Ice-Age Refugium.

Molecular ecology·2026

Same author

Proteomic analysis of dental enamel from 20 Homo naledi individuals shows no male markers.

Cell·2026

Same author

Genetic diversity of late Neanderthals in northwestern Europe.

Nature·2026

Same author

Lethal plague outbreaks in Lake Baikal hunter-gatherers 5,500 years ago.

Nature·2026

Same author

Faroese whole genomes provide insight into ancestry and recent selection.

eLife·2026

Same author

Population discontinuity in the Paris Basin linked to evidence of the Neolithic decline.

Nature ecology & evolution·2026

Same journal

Lactate as a Chemical Modification on Proteins and Metabolites.

Annual review of biochemistry·2026

Same journal

Nucleocytoplasmic Transport.

Annual review of biochemistry·2026

Same journal

Packaging of Single-Stranded RNA in Viruses and Virus-Like Particles.

Annual review of biochemistry·2026

Same journal

Shaping of the Infant Gut Microbiome by Milk Oligosaccharides.

Annual review of biochemistry·2026

Same journal

Proteostasis Deregulation by Metabolism Drives the Hallmarks of Cancer.

Annual review of biochemistry·2026

Same journal

JoAnne Stubbe's Radical Path: A Story of Passion, Curiosity, and Persistence.

Annual review of biochemistry·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 11, 2026

Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains

Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains

Published on: November 30, 2021

Ancient Biomolecules and Evolutionary Inference.

Enrico Cappellini¹, Ana Prohaska², Fernando Racimo¹

¹Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, 1350 Copenhagen, Denmark; email: ecappellini@snm.ku.dk , ewillerslev@snm.ku.dk.

Annual Review of Biochemistry

|May 1, 2018

Summary

This summary is machine-generated.

Ancient biomolecule research, including DNA, proteins, and lipids, has advanced significantly over 30 years. Modern techniques enable retrieval from challenging environments, revolutionizing evolutionary history studies.

Keywords:

ancient DNA ancient genomics ancient lipids ancient proteins paleogenomics paleoproteomics

More Related Videos

Internalization and Observation of Fluorescent Biomolecules in Living Microorganisms via Electroporation

Internalization and Observation of Fluorescent Biomolecules in Living Microorganisms via Electroporation

Published on: February 8, 2015

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3

Published on: December 27, 2010

Related Experiment Videos

Last Updated: Feb 11, 2026

Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains

Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains

Published on: November 30, 2021

Internalization and Observation of Fluorescent Biomolecules in Living Microorganisms via Electroporation

Internalization and Observation of Fluorescent Biomolecules in Living Microorganisms via Electroporation

Published on: February 8, 2015

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3

Published on: December 27, 2010

Area of Science:

Paleogenomics
Paleoproteomics
Paleolipidomics

Background:

Ancient biomolecule studies, including DNA, proteins, and lipids, have overcome initial challenges.
The field has expanded in sampling scope, data quality, and geographic reach.
Progress relies on technical innovations, improved sample selection, and computational methods.

Purpose of the Study:

To review the history and current status of ancient biomolecule research.
To highlight applications in evolutionary inference.
To discuss future directions in the field.

Main Methods:

Retrieval of ancient DNA, protein sequences, and lipid signatures.
Analysis of samples from diverse and challenging depositional environments.
Integration of advanced analytical and computational approaches.

Main Results:

Successful retrieval of biomolecules from progressively older and more challenging samples.
Increased sampling frequencies and spatial/temporal scope of studies.
Generation of larger and higher-quality datasets for evolutionary research.

Conclusions:

Ancient biomolecule research is now a robust field.
Technological advancements have enabled significant progress in understanding evolutionary history.
The field holds exciting future potential for evolutionary inference.