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Updated: Feb 11, 2026
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Less-Invasive Technique for Non-stabilized Mandibular Fracture in Mouse Models
Published on: September 27, 2024
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Gender differences in morphological and functional outcomes after mandibular setback surgery
Khaled Dahy1, Katsu Takahashi2, Kazuyuki Saito2
1Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan; Department of Otolaryngology-Head and Neck Surgery, Sohag University, Sohag, Egypt.
Summary
This study found that both isolated mandibular setback and bimaxillary surgery impact airway space, with gender-specific risks for obstructive sleep apnea (OSA). Compensatory mechanisms may mitigate these risks.
Area of Science:
- Oral and Maxillofacial Surgery
- Orthognathic Surgery
- Sleep Medicine
Background:
- Mandibular prognathism requires surgical correction, impacting facial morphology and airway.
- Gender-specific outcomes in orthognathic surgery are not fully understood.
- Obstructive sleep apnea (OSA) is a potential complication of airway changes post-surgery.
Purpose of the Study:
- To compare morphological and functional outcomes of isolated mandibular setback versus bimaxillary surgery.
- To investigate gender differences in surgical outcomes for mandibular prognathism.
- To assess changes in airway space and respiratory function after surgery.
Main Methods:
- Retrospective study of 52 patients undergoing isolated mandibular setback or bimaxillary surgery.
- Morphological analysis using cephalograms.
- Functional assessment via impulse oscillometry (IOS) and 3% oxygen desaturation index (ODI) measurements.
Main Results:
- Posterior airway space decreased in both sexes, with greater reduction in males after mandibular setback and females after bimaxillary surgery.
- Airway resistance (R20, R5) increased significantly more in males than females post-mandibular setback surgery.
- Gender dimorphism observed in airway changes and functional outcomes.
Conclusions:
- Males face higher OSA risk after mandibular setback surgery, while females face higher risk after bimaxillary surgery.
- Gender influences morphological and functional outcomes following orthognathic surgery.
- Compensatory physiological changes may protect against severe airway compromise.
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