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Updated: Feb 11, 2026

Isolation and Primary Culture of Mouse Aortic Endothelial Cells

Isolation and Primary Culture of Mouse Aortic Endothelial Cells

Published on: December 19, 2016

Massive organ embolization from primary aortic thrombosis.

Catarina Patrício¹, Mariana Marques Silva¹, Pedro Eduardo Silva¹

¹Departamento de Medicina Interna 2.3, Hospital de Santo António dos Capuchos, Centro Hospitalar Lisboa Central, Lisboa, Portugal.

Revista Portuguesa De Cardiologia

|May 1, 2018

Summary

This summary is machine-generated.

Primary aortic thrombosis caused multiple organ infarctions and limb ischemia in a patient. Systemic anticoagulation successfully resolved the aortic thrombus, highlighting its potential efficacy for this rare condition.

Keywords:

Angiotomografia computorizada Computed Tomography Angiography Enfartes multissistémicos Multi-Systemic Infarcts Primary aortic thrombosis Trombose primária da aorta

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Area of Science:

Vascular Surgery
Cardiology
Gastroenterology

Background:

Primary aortic thrombosis is a rare condition that can lead to serious embolic events.
Aortic atherosclerosis and intracardiac embolic sources are common causes of thrombosis, but were absent in this case.

Observation:

A 49-year-old woman presented with acute left foot arterial ischemia and abdominal pain.
Computed tomography angiography revealed hepatic, splenic, renal, and pancreatic infarctions, along with a splenic artery embolism and an aortic wall thrombus at the celiac trunk.

Findings:

The patient was diagnosed with primary aortic thrombosis, lacking typical risk factors like atherosclerosis.
Systemic anticoagulation therapy was initiated for the aortic thrombus.

Implications:

The case demonstrates successful resolution of aortic thrombus and associated infarctions with anticoagulation.
Close clinical follow-up is essential due to the risk of recurrence even with treatment and risk factor management.